Vol. 8 No. 1 (2017): Volume 8: Gene Editing and Personalized Medicine

Vol. 8 No. 1 (2017)

Published August 31, 2017
Volume 8: Gene Editing and Personalized Medicine

This volume explores the emerging world of gene editing and personalized medicine. Sub themes in this volume include: 

Clinical applications of "-omics" technologies in personalized medicine
The role of genome editing in health care
The social and ethical implications of genome editing

Full Issue
Volume 8

News

Logan Townsend
Page 6-Page 7
The ethics of genetic engineering
https://doi.org/10.29173/hsi242
pdf
Manreet Padwal
Page 8-Page 9
The CRISPR/Cas9 system in gene editing of cancer stem cells
https://doi.org/10.29173/hsi243
pdf
Daniel Robinson
Page 10-Page 11
Developing CRISPR-Cas9 as a therapeutic tool to treat inherited genetic disorders
https://doi.org/10.29173/hsi244
pdf
Puja Bagri
Page 12-Page 13
Utilizing genomic tools to characterize the tumour landscape of glioblastoma
https://doi.org/10.29173/hsi245
pdf
Sarah Trottier, Logan Townsend
Page 14-Page 15
Modifying the microbiome: A gateway to treat Type 2 diabetes?
https://doi.org/10.29173/hsi246
pdf

Ask an Expert

Ronald F. Carter
Page 60-Page 61
Do you believe that N-of-1 trials (a clinical trial in which a single patient is the entire trial), are appropriate to evaluate the effectiveness of genomic therapies for rare and/or common genetic disorders? Do gene-editing/targeting therapies have the potential to expedite the advancement of personalized medicine?
https://doi.org/10.29173/hsi223
pdf
Renaud F. Boulanger, Veronique Fraser, Lori Seller
Page 62-Page 63
Ethics guidelines and gene editing technology: the challenges of enforceability and legitimacy
https://doi.org/10.29173/hsi224
pdf
Andrew Emili
Page 64-Page 65
Disease ‘interactome’ maps that may one day point to NEW diagnostics
https://doi.org/10.29173/hsi225
pdf
Karen J. Jacob, Alice Virani
Page 66-Page 67
With the recent advents of gene-editing technologies, how can we establish ethical guidelines to prevent the exploitations of these technologies in applications that are outside of conventional medicine?”
https://doi.org/10.29173/hsi226
pdf

Spotlight on Careers

Pedrum Mohammadi-Shemirani
Page 69-Page 71
Interview with Dr. Viraj Mane: Manager at Ontario Genomics
https://doi.org/10.29173/hsi247
pdf
Pedrum Mohammadi-Shemirani
Page 72-Page 73
Interview with Dr. Angela McDonald: Manager at McKinsey & Company
https://doi.org/10.29173/hsi248
pdf
Pedrum Mohammadi-Shemirani
Page 74-Page 75
Interview with Dr. Kripa Raman: Research AsSOCiate at Cornerstone Research Group
https://doi.org/10.29173/hsi249
pdf
Pedrum Mohammadi-Shemirani
Page 76-Page 77
Interview with Dr. Laurence MacPhie: Partner at Bereskin & Parr LLP
https://doi.org/10.29173/hsi250
pdf
Pedrum Mohammadi-Shemirani
Page 78-Page 79
Interview with Dr. Alexis Carere: Manager at Ontario Genomics
https://doi.org/10.29173/hsi251
pdf

Main Submissions

Yichi Zhang, Aaron MacCosham
Page 18-Page 20
Cut, Repair, Stitch – How Close Are We to Molecular Surgery Performed Using Genome Editing Techniques?
https://doi.org/10.29173/hsi227
pdf
Michelle Yee, Alex Dragoman, John-Paul Oliveria
Page 21-Page 24
An Overview of CRISPR – From Germs to Giants
https://doi.org/10.29173/hsi228
pdf
Parastoo Boroumand, Farigol Hakem Zadeh
Page 25-Page 26
Next Steps in Cancer Therapy: Integration of Gene Editing in Inducible Pluripotent Stem Cells
https://doi.org/10.29173/hsi229
pdf
Love P. Sandhu, John F. Dawson
Page 27-Page 28
CRISPRs to Treat, Understand, and Prevent Disease
https://doi.org/10.29173/hsi230
pdf
Abirami Kirubarajan, Jia Lu, John-Paul Oliveria
Page 29-Page 31
Vectors Have Both Magnitude and Direction: Considerations for Viral versus Non-Viral Vectors in Gene Therapy
https://doi.org/10.29173/hsi231
pdf
Robert Ungard
Page 32-Page 33
NEW Developments in Human Embryonic Research Put Pressure on the 14-Day Rule
https://doi.org/10.29173/hsi232
pdf
Caleb Seward, Harry Li, John-Paul Oliveria
Page 34-Page 36
CRISPR and TALEN: Facilitating Tailored Genomes of the Future
https://doi.org/10.29173/hsi233
pdf
Ohood Alharbi
Page 37-Page 38
Clinical Application of Omics Technology in the History of Primary Lactose Intolerance
https://doi.org/10.29173/hsi234
pdf
Matthew Boroditsky, Mobeen Mubasher, John-Paul Oliveria
Page 39-Page 42
A Lens Into Mass Cytometry: A Multifaceted Technology Used to Delve Deep into Single-Cell Analysis
https://doi.org/10.29173/hsi235
pdf
Meghan Lofft
Page 43-Page 44
Heritable Genome Editing: Technological Innovation for Future Perspectives in Healthcare
https://doi.org/10.29173/hsi236
pdf
Jennifer Shuldiner
Page 45-Page 46
The personal side to genetic testing
https://doi.org/10.29173/hsi237
pdf
Abirami Kirubarajan, Emily Norris, John-Paul Oliveria
Page 47-Page 49
It’s In Your Genes: Recent Considerations in Germline versus Somatic Gene Therapy
https://doi.org/10.29173/hsi238
pdf
Parastoo Boroumand, Neshat Deljoomanesh, Farigol Hakem Zadeh
Page 50-Page 52
Query into the Future of Gene Editing: Possibilities and Apprehensions
https://doi.org/10.29173/hsi239
pdf
Moushumi Nath, Xinwen Zhu
Page 53-Page 55
The Predictive Power of Omics: Clinical Applications
https://doi.org/10.29173/hsi240
pdf
Spandana Amarthaluru, Michael Aw, John-Paul Oliveria
Page 56-Page 58
In Utero Gene Therapy: A Brave NEW World of Designer Babies?
https://doi.org/10.29173/hsi241
pdf