The landscape of nutrition advice is vast and full of misinformation. A primary source of nutrition advice in Canada comes from the Canadian Food Guide, however, many questions remain regarding the reach and accessibility of the food guide. Specifically, is the population most likely to receive and use this information, the population that needs it the most? Are there barriers to following this guide that Health Canada has failed to address? Is there evidence supporting the efficacy of this food guide in populations at risk for nutrition misinformation or diet-related preventable diseases? This commentary reviews the past research regarding efficacy of previous food guides and highlights potential barriers preventing equal and accessible use of Canada’s Food Guide.